What Is Cushing’s Syndrome?
Cushing’s Syndrome is when too much cortisol hormone is released into the body. The additional cortisol released into the body can cause havoc on the body.
Cushing’s Syndrome is also known as Hypercortisolism. Cushing’s Syndrome disease is more frequent in women than men. The most often seen age range for people with Cushing’s Syndrome is 25 to 40 years old.
Cushing’s Disease is the opposite of Adrenal Insufficiency.
Cushing’s Syndrome may be caused by:
- A tumor or tumors inside the body
- Consuming too much corticosteroid medications
Cushing’s Disease can be a difficult disease to diagnosis and treat. There is no single definitive test to diagnose Cushing Syndrome. The diagnosis of Cushing’s Syndrome involves a thorough physical examination and a review of your medical history and symptoms. These Laboratory Tests may help with a diagnosis:
- 24 hour urinary (free cortisol test)
- Midnight cortisol plasma and late evening salivary cortisol measurements,
low-dose dexamethasone suppression test (LDDST) (blood test)
Fortunately, the National Institute Of Health (NIH) published the PRKACA enzyme has been linked to severe form of Cushing’s Syndrome.
PRKACA enzyme code is regulated by the PRKAR1A. The PRKAR1A has numerous functions within the metabolism of the cell and had previously been found in a similar form of Cushing’s Syndrome. The new finding of the PRKACA enzyme links it’s pathway in Cushing’s Syndrome.
You can read more about the National Institute of Health (NIH) article about the PRKACA enzyme at: http://www.nih.gov/researchmatters/march2014/03102014cushing.htm
If you are diagnosed with Cushing’s Syndrome than the Treatment for Cushing Syndrome will depend on what is the cause of the problem. Your doctor may prescribe a medication that may help control cortisol production. If the additional cortisol surge is caused by a tumor (tumors) then tumor (tumors) may be removed.
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